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Everything posted by StormKnight
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For cell propagation, perhaps. This critter is able to keep itself immortal due to a cellular process, and keep tissues immortal. There are immortal cells, but they are usually not functional in a organism (cancer.) While the idea of making normal cells immortal would help research, (as most stable immortal cell cultures are derived from cancer cell lines, which have various other biochemical processes destroyed in the process,) as for alternative for stem cells, whose switches are basically in a default off position, who knows? Differentiation (the stem cell becoming a cell of a bone, liver, etc.,) versus immortality (a cell that can remain functional forever,) are two different processes in the cell itself, at least by current biochemical research. The jelly here, is made up of differentiated cells (by definition of a multicellular organism,) whose cells are immortal. Very interesting. On a side note, I am glad these jellyfish aren't armed with a sword-like appendage, and have heads. Unshielded electricity and underwater Quickening storms might be poor form. Though the idea of "There can be only one (jellyfish!)" would help the Japanese fishing industry.
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Well, post them. If you care enough to post, you should care enough to back what you post with evidence. The 71 hits from PubMed based on the search using the keywords in my original post were researched and reviewed and done in the last decade, debunking most of the evidence brought up in the 50's and 60's that it has no medical use (the definition of a substance on Schedule I.) Granted, I don't think it will be over-the-counter for a long time, if at all. Everything used in medicine is a two-sided coin. Everything. The question becomes is the other side worth the benefits of the side that is facing you. Current studies, in the case of pain and medical marijuana, the current research is pointing to the fact the other side is not as bad as was previously believed.
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So you are saying the research that is being done in the use of marijuana as a LEGALLY PRESCRIBED therapeutic pain management agent is bogus, despite the EVIDENCE-BASED MEDICINE hard data to the contrary? I noticed you haven't made comment on my previous post, listing a very small fraction of a large body of evidence that it does work for pain management when used with other pain meds. This was prescribed as a legal pain adjunct, and it kept him functional enough to keep being productive. So unless one is a practicing pain specialist or palliative care specialist who has peer-reviewed PUBLISHED data to prove the mounting data is wrong, I suggest that one would hold opinion until one can back it up with hard, published data.
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Well, if opinions don't matter, how about clinical research? The research and trials in marijuana and pain management is a growing body of knowledge: Therapeutics and clinical risk management,2008-Therapeutics and clinical risk management Current opinion in supportive and palliative care, 2007-Do cannabinoids have a role in cancer pain management? Best practice & research. Clinical endocrinology & metabolism, 2009-Use of cannabinoid receptor agonists in cancer therapy as palliative and curative agents. Trends in Pharmacological Sciences, 2009-Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb Endocannabinoids in the Retina: From Marijuana to Neuroprotection (free article access.) Current Status of Cannabis Treatment of Multiple Sclerosis with an Illustrative Case Presentation of a Patient with MS, Complex Vocal Tics, Paroxysmal Dystonia, and Marijuana Dependence Treated with Dronabinol (free article access.) Plant-Derived Cannabinoids Modulate the Activity of Transient Receptor Potential Channels of Ankyrin Type-1 and Melastatin Type-8 (free article access.) And this was me just punching in "marijuana cancer pain" into PubMed, which accesses the National Library of Medicine (NLM,) and NIH. While these are abstracts for the most part, the journals are available at any university library with medical and/or nursing schools. Those who are prescribing MM are treating it like a Schedule II drug, which, as I have stated in opinion before, will probably be the lowest we see it dropped when (more and more likely,) or if it gets off Schedule I. On Schedule II is fentanyl, a opioid that is 100 times more potent than morphine. It is also used in cancer pain, so we will use this as an example. Fentanyl, like opioid analgesics (morphine, codeine, dilaudid, etc.) bind to the most common receptor for pain, (mu-opioid receptors) in the nervous system. These are the same receptors that endorphins, our body's natural pain killers, work. Works great most of the time. The side effects are due to mu-opioid receptors being located outside the pain system as well, such as the basal nuclei (breathing centers, why they cause apnea,) the digestive system (reason they cause constipation, nausea.) THC, the active ingredient in MM, hits another receptor in the nervous system's pain relays (cannabinoid receptors.) They also attenuate pain. Since the receptors are less common throughout the body, there is a better side effect profile. Used in conjunction with opioids, MM allow for better pain control and higher functionality. And it is fast, since it is inhaled, it bypasses the liver and metabolism, and goes right to the brain. There is a saying; "All pain can be controlled. It is how much functionality you wish to have." The current trend in pain treatment, especially palliative care, is to keep the patient as high functional as long as possible. The reason? NO ONE wants to die in a hospital. Depending on where the cancer is and how much anatomy it destroys, to maintain daily activity right up until the end is NOT UNREASONABLE. And it is a VERY SERIOUS CONSIDERATION. If a patient with terminal cancer is able to do something they like up to the instant of death, whether golfing, playing with their kids/grandkids, or working a job (as this guy may have wanted to do,) and it is legally possible use it (last placed I worked it wasn't,) then more power to him. We had one patient play a round of golf the day before he died, which was something that he liked to do. He was on fentanyl patches, some oral morphine as needed, and a joint before leaving for the golf course. So, by hitting two receptors in the pain pathway, we pain specialists are able to keep terminal patients living productive and happy lives right up until the end, rather than wasting days in a bed waiting for the inevitable.
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"Mongo only pawn in game of life."
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I would like to be between a blonde, brunette, and redhead. Though, with my past experiences with blondes, I would go for the latter two if choosing.
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Words of wisdom from Dad... NSFW
StormKnight replied to a topic in Movies, Books, Art, TV, Gaming and Computers
"Science and Mother Nature are in a marriage where Science is always surprised to come home and find Mother Nature blowing the neighbor." "Sprain, huh? Did you go to medical school?... Well I did, so spare me your dog-shit diagnosis and lemme look at your ankle." "War hero? No. I was a doc in Vietnam. My job was to say "This is what happens when you screw a hooker, kid. Put this cream on your pecker." "I'm having a Makers Mark, you want one? What? 7up? I ain't mixing fucking makers with 7up. Might as well put a lil' fucking umbrella in it" Can I be that cynical when I'm old...? wait. Never mind. I want to meet this guy..lol -
strangely awake and wanting to be productive at this hour...
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WTD: an old computer monitor
StormKnight replied to Head Wreck's topic in General Promotion & Want Ads
HW. Got a 17-inch crt at home that I could get up to her. Just using it to run a g4 cube that I don't power up often. -
Must have better goggles than I do. Even drunk I don't think I can translate that.
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Not bad at all, good sir. Remind me to tell you my "Women-Country's Sports Car" joke. In a PM, it is kind of wrong...lol.
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Woman wants to be the world's largest woman.
StormKnight replied to StormKnight's topic in Health & Well-Being
Heard about that. That is one hell of a foreign body to have in a decubitus ulcer (which is what I suspected happened when she sat there in one place for 3 years. Skin breakdown and assimilation of the seat.) -
Full Metal Alchemist Brotherhood
StormKnight replied to Darkmatter's topic in Movies, Books, Art, TV, Gaming and Computers
No idea. There was a speedsub fansub group out there working on it, but it appears Funimation is going to put it out domestically soon. I think it is still in production in Japan. -
Full Metal Alchemist Brotherhood
StormKnight replied to Darkmatter's topic in Movies, Books, Art, TV, Gaming and Computers
Brotherhood actually from what my anime sources tell me, is supposed to be more like the manga. The origin story is the same, but there will be more faithfulness to the manga. -
Never had a problem with my apex seals, nor did people in my old group, and most ran stock apex seals. I have yet to hear reports of the RENESIS having issues when put to forced air induction, though I am out of the loop. Most problems I have seen, which were solved with the advent of the solenoid switch block in the late 90's-2002, was the vacuum system running the twin sequential turbos (which was always my favorite, and I would make the mod of using the solenoid switch block.) The original one had 72 connections, and I believe 10 or so solenoids and 3 check valves. The advent of the block cut the complexity of the switching system by 75% But there is talk of a single unit turbo for induction.
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Try Heifetz playing the first movement of the Beethoven in D. The cadenzas, (which I consider the best and ones that best reflect the themes in the first movement,) were written by both Heifetz and Leopold Auer. And the Gavotte en Rondeau of the 3rd Partita is an example of why he is known as the Grand Master of pitch and timing of the 20th century. A lot of modern violinists cry that they can't get as perfect as Heifetz even now. A teacher once told the story of someone finding him practicing a simple scale in first position (not by octaves, not in a different position until it hit A on the E string,) with pitch perfect tone in a practice room, not realizing it was Heifetz until they knocked on the door and he opened it. Simple fundamentals of music, consistently reviewed by The Master just to warm up, before going off on one of the above pieces.
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Gee, aren't *I* the Hawaiian Ball of testosterone poisoning today.
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If you want to be like Chuck Norris - This is what you'll drive:
StormKnight replied to Msterbeau's topic in Other Stuff
"Chuck Norris doesn't drive balls to the wall. The wall asks for the honor to be close to Chuck Norris' testes when he drives." -
If you want to be like Chuck Norris - This is what you'll drive:
StormKnight replied to Msterbeau's topic in Other Stuff
Nice. -
There is that, but my big one is that it seats more than 2 people. Call me a sports car purist, but I when I commune at speeds and pulling g's in turns, I want to share it with only one friend, or keep the experience to myself. The extra people in the back throw off the weight balance fore and aft. Not to mention that when I really fly, I can only deal with one person screaming in terror at once (I am usually the one screaming "Banzai!" a Correllian War Cry, or the action quote of the day.) If it seats more than three (in deference to the Vector W-2 that seated three across,) it is a sports sedan, not a sports car. ... Did I fail to mention I am a bit of an adrenaline junkie? Anyway, as for fuel economy, now that the ports to the side housing with the RENESIS engine, it has gone up, and they still tune them. Though in my FD with the REW and rotor housing exhaust, I was able to pull anywhere from 27-30mpg hwy, even with a little "spirited" driving. City always stunk at 13.