I actually miss Jacobson's. I didn't shop there, but I remember it being a really upscale store and I was in awe of it as a kid.
Why don't we have Friendly's in Michigan anymore? They have them in rural New York and Ohio. I want a peanutty sundae and a hot dog served on grilled Texas toast.
No one else probably remembers my favorite two fast food restaurants as a child: Burger Chef (the originator of the kids' meal) and Taco Grande (which predated Taco Bell and was BETTER, more like El Charro, if you've ever been there).
Edit: I guess a few of you DO remember Burger Chef!
My mom used to always shop at Chattam's grocery. She'd pass by a Farmer Jack and Kroger to get there. We'd buy the gallon tub of Velvet peanut butter and I would sneak grapes and green beans from the produce section. Mom used to come in with sheets and sheets of savings stamps she could trade in for household items. Pretty much all the grocery chains had similar schemes.
A&P grocery stores are still going in some parts of the country, I think, but not here. It's also rare to find an IGA.
F&M, Perry and Arbor drug stores used to be regular stops.
Pace before it became Sam's Club: the original warehouse wholesaler. I don't miss it that much. Costco is awesome.
I remember when Sears was an essential store before Meijer and Target and Walmart usurped most of their customers. Yeah, Sears is still around, but in a much lamer incarnation.
And now, I will miss Borders; it's affiliates--not so much.
Edit to add: I really miss Monty's, Trixie's, Roadrunner Inn (wasn't that the name? that's where I was heading in my profile pic), and Bittersweet. Even moreso now that Blair and Sean are both gone (Simon Bar Sinister knows who I mean).