I'm right handed for the most part, although I can bat left handed and I do shuffle cards and brush my hair left handed.
My oldest son is left handed and I couldn't teach him to tie his shoes... my niece managed to teach him in less than 5 minutes.
There's a store in my local mall that sells a bunch of things that are made for left handed people. Can openers, scissors, pencils, notebooks, and a bunch of other things.